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Predicting the safety and efficacy of buffer therapy to raise tumour pHe: an integrative modelling study

BACKGROUND: Clinical positron emission tomography imaging has demonstrated the vast majority of human cancers exhibit significantly increased glucose metabolism when compared with adjacent normal tissue, resulting in an acidic tumour microenvironment. Recent studies demonstrated reducing this acidit...

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書誌詳細
主要な著者: Martin, N K, Robey, I F, Gaffney, E A, Gillies, R J, Gatenby, R A, Maini, P K
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314784/
https://ncbi.nlm.nih.gov/pubmed/22382688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.58
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