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Predicting the safety and efficacy of buffer therapy to raise tumour pHe: an integrative modelling study
BACKGROUND: Clinical positron emission tomography imaging has demonstrated the vast majority of human cancers exhibit significantly increased glucose metabolism when compared with adjacent normal tissue, resulting in an acidic tumour microenvironment. Recent studies demonstrated reducing this acidit...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2012
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3314784/ https://ncbi.nlm.nih.gov/pubmed/22382688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.58 |
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