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Leaky Vessels as a Potential Source of Stromal Acidification in Tumours
Malignant tumours are characterised by higher rates of acid production and a lower extracellular pH than normal tissues. Previous mathematical modelling has indicated that the tumour-derived production of acid leads to a gradient of low pH in the interior of the tumour extending to a normal pH in th...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2963718/ https://ncbi.nlm.nih.gov/pubmed/20699102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2010.07.041 |
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