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A Mathematical Model of Tumour and Blood pHe Regulation: The [Formula: see text] Buffering System
Malignant tumours are characterised by a low, acidic extracellular pH (pHe) which facilitates invasion and metastasis. Previous research has proposed the potential benefits of manipulating systemic pHe, and recent experiments have highlighted the potential for buffer therapy to raise tumour pHe, pre...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3045481/ https://ncbi.nlm.nih.gov/pubmed/21167185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mbs.2010.12.002 |
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