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Function of the Active Site Lysine Autoacetylation in Tip60 Catalysis
The 60-kDa HIV-Tat interactive protein (Tip60) is a key member of the MYST family of histone acetyltransferases (HATs) that plays critical roles in multiple cellular processes. We report here that Tip60 undergoes autoacetylation at several lysine residues, including a key lysine residue (i.e. Lys-32...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3314657/ https://ncbi.nlm.nih.gov/pubmed/22470428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032886 |
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