Regulation of hepatic LDL receptors by mTORC1 and PCSK9 in mice

Individuals with type 2 diabetes have an increased risk of atherosclerosis. One factor underlying this is dyslipidemia, which in hyperinsulinemic subjects with early type 2 diabetes is typically characterized by increased VLDL secretion but normal LDL cholesterol levels, possibly reflecting enhanced...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ai, Ding, Chen, Chiyuan, Han, Seongah, Ganda, Anjali, Murphy, Andrew J., Haeusler, Rebecca, Thorp, Edward, Accili, Domenico, Horton, Jay D., Tall, Alan R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314476/
https://ncbi.nlm.nih.gov/pubmed/22426206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61919
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