RhoGDI2 suppresses lung metastasis in mice by reducing tumor versican expression and macrophage infiltration

Half of patients with muscle-invasive bladder cancer develop metastatic disease, and this is responsible for most of the deaths from this cancer. Low expression of RhoGTP dissociation inhibitor 2 (RhoGDI2; also known as ARHGDIB and Ly-GDI) is associated with metastatic disease in patients with muscl...

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Bibliografiske detaljer
Main Authors: Said, Neveen, Sanchez-Carbayo, Marta, Smith, Steven C., Theodorescu, Dan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314474/
https://ncbi.nlm.nih.gov/pubmed/22406535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61392
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