Rictor regulates cell migration by suppressing RhoGDI2

Rictor and its binding partner Sin1 are indispensable components of mTORC2 (mammalian Target of Rapamycin Complex 2). The mTORC2 signaling complex functions as the regulatory kinase of the distinct members of AGC kinase family known to regulate cell proliferation and survival. In the early chemotaxi...

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Hlavní autoři: Agarwal, Nitin K., Chen, Chien-Hung, Cho, Hyojin, Boulbès, Delphine R., Spooner, Eric, Sarbassov, Dos D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3470753/
https://ncbi.nlm.nih.gov/pubmed/22777355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.287
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