Islet β-Cell Endoplasmic Reticulum Stress Precedes the Onset of Type 1 Diabetes in the Nonobese Diabetic Mouse Model

Type 1 diabetes is preceded by islet β-cell dysfunction, but the mechanisms leading to β-cell dysfunction have not been rigorously studied. Because immune cell infiltration occurs prior to overt diabetes, we hypothesized that activation of inflammatory cascades and appearance of endoplasmic reticulu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Tersey, Sarah A., Nishiki, Yurika, Templin, Andrew T., Cabrera, Susanne M., Stull, Natalie D., Colvin, Stephanie C., Evans-Molina, Carmella, Rickus, Jenna L., Maier, Bernhard, Mirmira, Raghavendra G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2012
Assuntos:
Islet Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314371/
https://ncbi.nlm.nih.gov/pubmed/22442300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1293
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados