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Translational Control of Inducible Nitric Oxide Synthase by p38 MAPK in Islet β-Cells
The MAPKs are transducers of extracellular signals such as proinflammatory cytokines. In islet β-cells, cytokines acutely activate expression of the Nos2 gene encoding inducible nitric oxide synthase (iNOS), which ultimately impairs insulin release. Because iNOS production can also be regulated post...
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| Main Authors: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Endocrine Society
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3683810/ https://ncbi.nlm.nih.gov/pubmed/23250488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1230 |
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