Peroxisome Proliferator-Activated Receptor γ Activation Restores Islet Function in Diabetic Mice through Reduction of Endoplasmic Reticulum Stress and Maintenance of Euchromatin Structure

The nuclear receptor peroxisome proliferator-activated receptor γ (PPAR-γ) is an important target in diabetes therapy, but its direct role, if any, in the restoration of islet function has remained controversial. To identify potential molecular mechanisms of PPAR-γ in the islet, we treated diabetic...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Evans-Molina, Carmella, Robbins, Reiesha D., Kono, Tatsuyoshi, Tersey, Sarah A., Vestermark, George L., Nunemaker, Craig S., Garmey, James C., Deering, Tye G., Keller, Susanna R., Maier, Bernhard, Mirmira, Raghavendra G.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology (ASM) 2009
Θέματα:
Articles
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663298/
https://ncbi.nlm.nih.gov/pubmed/19237535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01179-08
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