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Methyltransferase Set7/9 Maintains Transcription and Euchromatin Structure at Islet-Enriched Genes
OBJECTIVE—The activation of β-cell genes, particularly of those encoding preproinsulin, requires an appropriate euchromatin (or “open”) DNA template characterized by hypermethylation of Lys4 of histone H3. We hypothesized that this modification is maintained in islet β-cells by the action of the his...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Diabetes Association
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2606870/ https://ncbi.nlm.nih.gov/pubmed/18984737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-1150 |
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