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A Broadly Cross-Reactive Monoclonal Antibody Against an Epitope on the N-terminus of Meningococcal fHbp

Meningococcal factor H binding protein (fHbp) is an important vaccine antigen for prevention of disease caused by capsular group B strains. The protein has been sub-classified into three variant groups. Most anti-fHbp antibodies are variant group-specific and recognize epitopes on the C-terminal dom...

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Detalhes bibliográficos
Main Authors: Vu, David M., Pajon, Rolando, Reason, Donald C., Granoff, Dan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314305/
https://ncbi.nlm.nih.gov/pubmed/22461972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00341
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