Second-hit kinetic perturbations reveal structural features of the domain IV S6 segment associated with fast inactivation

Lignende værker

• Double mutant gating perturbation analysis predicts a high conformational stability of the domain IV S6 segment of the voltage-gated Na(+ )channel
  af: Cervenka, René, et al.
  Udgivet: (2009)
• The permanently charged lidocaine analogue QX222 acts as a blocker from the intracellular side and as an inactivation modulator from the extracellular side in a mutant Na(V)1.4 channel
  af: Lukács, Péter, et al.
  Udgivet: (2010)
• From frog oocytes to mammalian cells: substantial differences in modulation of Na(V)1.4 channel slow kinetic behaviour by the β1 subunit
  af: Lukács, Péter, et al.
  Udgivet: (2009)
• A molecular switch between the outer and the inner vestibules of the voltage-gated Na(+) channel
  af: Cervenka, René, et al.
  Udgivet: (2010)
• Distinct modulation of inactivation by a residue in the pore domain of voltage-gated Na(+) channels: mechanistic insights from recent crystal structures
  af: Cervenka, Rene, et al.
  Udgivet: (2018)