The permanently charged lidocaine analogue QX222 acts as a blocker from the intracellular side and as an inactivation modulator from the extracellular side in a mutant Na(V)1.4 channel

Схожие документы

• Differential modulation of rNa(V)1.4 channel inactivated states by lidocaine and its charged analogue QX222
  по: Lukács, Péter, et al.
  Опубликовано: (2011)
• From frog oocytes to mammalian cells: substantial differences in modulation of Na(V)1.4 channel slow kinetic behaviour by the β1 subunit
  по: Lukács, Péter, et al.
  Опубликовано: (2009)
• A molecular switch between the outer and the inner vestibules of the voltage-gated Na(+) channel
  по: Cervenka, René, et al.
  Опубликовано: (2010)
• Double mutant gating perturbation analysis predicts a high conformational stability of the domain IV S6 segment of the voltage-gated Na(+ )channel
  по: Cervenka, René, et al.
  Опубликовано: (2009)
• Second-hit kinetic perturbations reveal structural features of the domain IV S6 segment associated with fast inactivation
  по: Cervenka, René, et al.
  Опубликовано: (2008)