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Orphan Nuclear Receptor Nur77 Promotes Acute Kidney Injury and Renal Epithelial Apoptosis

Nur77 and its family members Nurr1 and Nor-1 are inducible orphan nuclear receptors that orchestrate cellular responses to diverse extracellular signals. In epithelia, Nur77 can act as a potent proapoptotic molecule in response to cellular stress, suggesting a possible role for this nuclear receptor...

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מידע ביבליוגרפי
Main Authors: Balasubramanian, Savithri, Jansen, Marcel, Valerius, M. Todd, Humphreys, Benjamin D., Strom, Terry B.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Nephrology 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312507/
https://ncbi.nlm.nih.gov/pubmed/22343121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011070646
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