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Transient depletion of B cells in young mice results in activation of regulatory T cells that inhibit development of autoimmune disease in adults

B-cell depletion therapy can be effective for treating B-cell lymphomas as well as many human and murine autoimmune diseases. B-cell-deficient mice are normally resistant to spontaneous autoimmune thyroiditis (SAT), but they develop SAT if regulatory T cells are transiently depleted during the first...

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Detaylı Bibliyografya
Asıl Yazarlar: Yu, Shiguang, Ellis, Jason S., Dunn, Robert, Kehry, Marilyn R., Braley-Mullen, Helen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312073/
https://ncbi.nlm.nih.gov/pubmed/22298883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxs003
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