β-Catenin–SOX2 signaling regulates the fate of developing airway epithelium

Wnt–β-catenin signaling regulates cell fate during organ development and postnatal tissue maintenance, but its contribution to specification of distinct lung epithelial lineages is still unclear. To address this question, we used a Cre recombinase (Cre)-LoxP approach to activate canonical Wnt signal...

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Autores principales: Hashimoto, Shuichi, Chen, Huaiyong, Que, Jianwen, Brockway, Brian L., Drake, Jeffrey A., Snyder, Joshua C., Randell, Scott H., Stripp, Barry R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Company of Biologists 2012
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311930/
https://ncbi.nlm.nih.gov/pubmed/22421361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.092734
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