Down-Regulation of the Canonical Wnt β-Catenin Pathway in the Airway Epithelium of Healthy Smokers and Smokers with COPD

BACKGROUND: The Wnt pathway mediates differentiation of epithelial tissues; depending on the tissue types, Wnt can either drive or inhibit the differentiation process. We hypothesized that key genes in the Wnt pathway are suppressed in the human airway epithelium under the stress of cigarette smokin...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Rui, Ahmed, Joumana, Wang, Guoqing, Hassan, Ibrahim, Strulovici-Barel, Yael, Hackett, Neil R., Crystal, Ronald G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072378/
https://ncbi.nlm.nih.gov/pubmed/21490961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014793
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