β-Catenin–SOX2 signaling regulates the fate of developing airway epithelium

Wnt–β-catenin signaling regulates cell fate during organ development and postnatal tissue maintenance, but its contribution to specification of distinct lung epithelial lineages is still unclear. To address this question, we used a Cre recombinase (Cre)-LoxP approach to activate canonical Wnt signal...

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Detalhes bibliográficos
Main Authors: Hashimoto, Shuichi, Chen, Huaiyong, Que, Jianwen, Brockway, Brian L., Drake, Jeffrey A., Snyder, Joshua C., Randell, Scott H., Stripp, Barry R.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311930/
https://ncbi.nlm.nih.gov/pubmed/22421361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.092734
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