Rare SOX2(+) Airway Progenitor Cells Generate KRT5(+) Cells that Repopulate Damaged Alveolar Parenchyma following Influenza Virus Infection

Recent studies have implicated keratin 5 (KRT5)(+) cells in repopulation of damaged lung tissue following severe H1N1 influenza virus infection. However, the origins of the cells repopulating the injured alveolar region remain controversial. We sought to determine the cellular dynamics of lung repai...

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Bibliographic Details
Published in:Stem Cell Reports
Main Authors: Ray, Samriddha, Chiba, Norika, Yao, Changfu, Guan, Xiangrong, McConnell, Alicia M., Brockway, Brian, Que, Loretta, McQualter, Jonathan L., Stripp, Barry R.
Format: Artigo
Language:Inglês
Published: Elsevier 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5106521/
https://ncbi.nlm.nih.gov/pubmed/27773701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.09.010
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