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A simple method for the solid phase synthesis of oligodeoxynucleotides containing O4-alkylthymine.

A route to prepare the cyanoethyl-phosphoramidite monomer of O4-alkylthymine and a method for the routine solid-phase synthesis of oligodeoxynucleotides containing O4-alkylthymine are described. This method has been used to make DNA sequences up to 48 bases in length. The amino function of the adeni...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Xu, Y Z, Swann, P F
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1990
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC331160/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2377451/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.14.4061
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