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A simple method for the solid phase synthesis of oligodeoxynucleotides containing O4-alkylthymine.
A route to prepare the cyanoethyl-phosphoramidite monomer of O4-alkylthymine and a method for the routine solid-phase synthesis of oligodeoxynucleotides containing O4-alkylthymine are described. This method has been used to make DNA sequences up to 48 bases in length. The amino function of the adeni...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1990
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC331160/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2377451/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.14.4061 |
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