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Solid-Phase Synthesis of Oligodeoxynucleotides Containing N(4)-[2-(t-butyldisulfanyl)ethyl]-5-methylcytosine Moieties

An efficient route for the synthesis of the phosphoramidite derivative of 5-methylcytosine bearing a tert-butylsulfanyl group protected thiol is described. This building block is used for the preparation of oligonucleotides carrying a thiol group at the nucleobase at the internal position of a DNA s...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Pérez-Rentero, Sónia, Garibotti, Alejandra V., Eritja, Ramón
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6257692/
https://ncbi.nlm.nih.gov/pubmed/20720521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules15085692
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