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Solid-phase synthesis of biaryl bicyclic peptides containing a 3-aryltyrosine or a 4-arylphenylalanine moiety

A methodology for the solid-phase synthesis of biaryl bicyclic peptides containing a Phe-Phe, a Phe-Tyr or a Tyr-Tyr motif has been devised. This approach comprises two key steps. The first one involves the cyclization of a linear peptidyl resin containing the corresponding halo- and boronoamino aci...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Ng-Choi, Iteng, Oliveras, Àngel, Feliu, Lidia, Planas, Marta
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6444451/
https://ncbi.nlm.nih.gov/pubmed/30992724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.72
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