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A simple method for the solid phase synthesis of oligodeoxynucleotides containing O4-alkylthymine.

A route to prepare the cyanoethyl-phosphoramidite monomer of O4-alkylthymine and a method for the routine solid-phase synthesis of oligodeoxynucleotides containing O4-alkylthymine are described. This method has been used to make DNA sequences up to 48 bases in length. The amino function of the adeni...

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Détails bibliographiques
Auteurs principaux: Xu, Y Z, Swann, P F
Format: Artigo
Langue:Inglês
Publié: 1990
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC331160/
https://ncbi.nlm.nih.gov/pubmed/2377451
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