EP(2) and EP(4) receptors on muscularis resident macrophages mediate LPS-induced intestinal dysmotility via iNOS upregulation through cAMP/ERK signals

Intestinal resident macrophages play an important role in gastrointestinal dysmotility by producing prostaglandins (PGs) and nitric oxide (NO) in inflammatory conditions. The causal correlation between PGs and NO in gastrointestinal inflammation has not been elucidated. In this study, we examined th...

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Detaylı Bibliyografya
Asıl Yazarlar: Tajima, Tsuyoshi, Murata, Takahisa, Aritake, Kosuke, Urade, Yoshihiro, Michishita, Masaki, Matsuoka, Toshiyuki, Narumiya, Shuh, Ozaki, Hiroshi, Hori, Masatoshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2012
Konular:
Inflammation/Immunity/Mediators
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311437/
https://ncbi.nlm.nih.gov/pubmed/22159280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00264.2011
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