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Prostagladin D(2) is a mast cell-derived antiangiogenic factor in lung carcinoma

It is well established that prostaglandins (PGs) are involved in tumor angiogenesis and growth, yet the role of prostaglandin D(2) (PGD(2)) remains virtually unknown. Here, we show that host hematopoietic PGD(2) synthase (H-PGDS) deficiency enhances Lewis lung carcinoma (LLC) progression, accompanie...

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Detalhes bibliográficos
Main Authors: Murata, Takahisa, Aritake, Kosuke, Matsumoto, Shigeko, Kamauchi, Shinya, Nakagawa, Takayuki, Hori, Masatoshi, Momotani, Eiichi, Urade, Yoshihiro, Ozaki, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241753/
https://ncbi.nlm.nih.gov/pubmed/22106279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110011108
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