Prostagladin D(2) is a mast cell-derived antiangiogenic factor in lung carcinoma

It is well established that prostaglandins (PGs) are involved in tumor angiogenesis and growth, yet the role of prostaglandin D(2) (PGD(2)) remains virtually unknown. Here, we show that host hematopoietic PGD(2) synthase (H-PGDS) deficiency enhances Lewis lung carcinoma (LLC) progression, accompanie...

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Autori principali: Murata, Takahisa, Aritake, Kosuke, Matsumoto, Shigeko, Kamauchi, Shinya, Nakagawa, Takayuki, Hori, Masatoshi, Momotani, Eiichi, Urade, Yoshihiro, Ozaki, Hiroshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241753/
https://ncbi.nlm.nih.gov/pubmed/22106279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110011108
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