Prostagladin D(2) is a mast cell-derived antiangiogenic factor in lung carcinoma

It is well established that prostaglandins (PGs) are involved in tumor angiogenesis and growth, yet the role of prostaglandin D(2) (PGD(2)) remains virtually unknown. Here, we show that host hematopoietic PGD(2) synthase (H-PGDS) deficiency enhances Lewis lung carcinoma (LLC) progression, accompanie...

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Main Authors: Murata, Takahisa, Aritake, Kosuke, Matsumoto, Shigeko, Kamauchi, Shinya, Nakagawa, Takayuki, Hori, Masatoshi, Momotani, Eiichi, Urade, Yoshihiro, Ozaki, Hiroshi
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2011
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241753/
https://ncbi.nlm.nih.gov/pubmed/22106279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110011108
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