Antiproliferative small-molecule inhibitors of transcription factor LSF reveal oncogene addiction to LSF in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Despite the prevalence of HCC, there is no effective, systemic treatment. The transcription factor LSF is a promising protein target for chemotherapy; it is highly expressed in HCC patient samples and cell lines, and promotes...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Grant, Trevor J., Bishop, Joshua A., Christadore, Lisa M., Barot, Girish, Chin, Hang Gyeong, Woodson, Sarah, Kavouris, John, Siddiq, Ayesha, Gredler, Rachel, Shen, Xue-Ning, Sherman, Jennifer, Meehan, Tracy, Fitzgerald, Kevin, Pradhan, Sriharsa, Briggs, Laura A., Andrews, William H., Sarkar, Devanand, Schaus, Scott E., Hansen, Ulla
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2012
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311344/
https://ncbi.nlm.nih.gov/pubmed/22396589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121601109
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