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Sonic Hedgehog-activated engineered blood vessels enhance bone tissue formation

Large bone defects naturally regenerate via a highly vascularized tissue which progressively remodels into cartilage and bone. Current approaches in bone tissue engineering are restricted by delayed vascularization and fail to recapitulate this stepwise differentiation toward bone tissue. Here, we u...

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Podrobná bibliografie
Hlavní autoři: Rivron, Nicolas C., Raiss, Christian C., Liu, Jun, Nandakumar, Anandkumar, Sticht, Carsten, Gretz, Norbert, Truckenmüller, Roman, Rouwkema, Jeroen, van Blitterswijk, Clemens A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311342/
https://ncbi.nlm.nih.gov/pubmed/22388744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117627109
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