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Sonic Hedgehog-activated engineered blood vessels enhance bone tissue formation
Large bone defects naturally regenerate via a highly vascularized tissue which progressively remodels into cartilage and bone. Current approaches in bone tissue engineering are restricted by delayed vascularization and fail to recapitulate this stepwise differentiation toward bone tissue. Here, we u...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3311342/ https://ncbi.nlm.nih.gov/pubmed/22388744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117627109 |
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