Sonic Hedgehog-activated engineered blood vessels enhance bone tissue formation

Large bone defects naturally regenerate via a highly vascularized tissue which progressively remodels into cartilage and bone. Current approaches in bone tissue engineering are restricted by delayed vascularization and fail to recapitulate this stepwise differentiation toward bone tissue. Here, we u...

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Главные авторы: Rivron, Nicolas C., Raiss, Christian C., Liu, Jun, Nandakumar, Anandkumar, Sticht, Carsten, Gretz, Norbert, Truckenmüller, Roman, Rouwkema, Jeroen, van Blitterswijk, Clemens A.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2012
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311342/
https://ncbi.nlm.nih.gov/pubmed/22388744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117627109
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