Sonic Hedgehog-activated engineered blood vessels enhance bone tissue formation

Large bone defects naturally regenerate via a highly vascularized tissue which progressively remodels into cartilage and bone. Current approaches in bone tissue engineering are restricted by delayed vascularization and fail to recapitulate this stepwise differentiation toward bone tissue. Here, we u...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rivron, Nicolas C., Raiss, Christian C., Liu, Jun, Nandakumar, Anandkumar, Sticht, Carsten, Gretz, Norbert, Truckenmüller, Roman, Rouwkema, Jeroen, van Blitterswijk, Clemens A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2012
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311342/
https://ncbi.nlm.nih.gov/pubmed/22388744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117627109
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