Inhibition of cell migration by PITENINs: the role of ARF6

We have previously reported the development of small molecule phosphatidylinositol-3,4,5-trisphosphate (PIP3) antagonists (PITs) that block pleckstrin homology (PH) domain interaction, including activation of Akt, and show anti-tumor potential. Here we show that the same molecules inhibit growth fac...

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Autori principali: Miao, Benchun, Skidan, Igor, Yang, Jinsheng, You, Zerong, Fu, Xueyan, Famulok, Michael, Schaffhausen, Brian, Torchilin, Vladimir, Yuan, Junying, Degterev, Alexei
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310973/
https://ncbi.nlm.nih.gov/pubmed/22179837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.593
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