Optimization of the anti-cancer activity of phosphatidylinositol-3 kinase pathway inhibitor PITENIN-1: switching a thiourea with 1,2,3-triazole

We previously reported encouraging in vitro and in vivoanti-cancer activity of N-((3-chloro-2-hydroxy-5-nitrophenyl)carbamothioyl)benzamide (termed PITENIN-1). In the current work, we describe the structure-activity relationship study of PIT-1 series, based on the replacement of central thiourea uni...

全面介紹

Na minha lista:
書目詳細資料
發表在:Medchemcomm
Main Authors: Kommagalla, Yadagiri, Cornea, Sinziana, Riehle, Robert, Torchilin, Vladimir, Degterev, Alexei, Ramana, Chepuri V.
格式: Artigo
語言:Inglês
出版: 2014
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259262/
https://ncbi.nlm.nih.gov/pubmed/25505943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4MD00109E
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍