Crystallization and X-ray structure analysis of a thermostable penicillin G acylase from Alcaligenes faecalis

The enzyme penicillin G acylase (EC 3.5.1.11) catalyzes amide-bond cleavage in benzylpenicillin (penicillin G) to yield 6-aminopenicillanic acid, an intermediate chemical used in the production of semisynthetic penicillins. A thermostable penicillin G acylase from Alcaligenes faecalis (AfPGA) has be...

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Detalhes bibliográficos
Main Authors: Varshney, Nishant Kumar, Suresh Kumar, R., Ignatova, Zoya, Prabhune, Asmita, Pundle, Archana, Dodson, Eleanor, Suresh, C. G.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2012
Assuntos:
Structural Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310528/
https://ncbi.nlm.nih.gov/pubmed/22442220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111053930
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