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Structure mediation in substrate binding and post-translational processing of penicillin acylases: Information from mutant structures of Kluyvera citrophila penicillin G acylase

Penicillin acylases are industrially important enzymes for the production of 6-APA, which is used extensively in the synthesis of secondary antibiotics. The enzyme translates into an inactive single chain precursor that subsequently gets processed by the removal of a spacer peptide connecting the ch...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Protein Sci
Egile Nagusiak: Chand, Deepak, Varshney, NishantKumar, Ramasamy, Sureshkumar, Panigrahi, Priyabrata, Brannigan, James A, Wilkinson, Anthony J, Suresh, C G
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley & Sons, Ltd 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594665/
https://ncbi.nlm.nih.gov/pubmed/26243007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2761
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