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Iterative approach to computational enzyme design

A general approach for the computational design of enzymes to catalyze arbitrary reactions is a goal at the forefront of the field of protein design. Recently, computationally designed enzymes have been produced for three chemical reactions through the synthesis and screening of a large number of va...

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Detalhes bibliográficos
Main Authors: Privett, Heidi K., Kiss, Gert, Lee, Toni M., Blomberg, Rebecca, Chica, Roberto A., Thomas, Leonard M., Hilvert, Donald, Houk, Kendall N., Mayo, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309769/
https://ncbi.nlm.nih.gov/pubmed/22357762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118082108
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