An iterative computational design approach to increase the thermal endurance of a mesophilic enzyme

BACKGROUND: Strategies for maximizing the microbial production of bio-based chemicals and fuels include eliminating branched points to streamline metabolic pathways. While this is often achieved by removing key enzymes, the introduction of nonnative enzymes can provide metabolic shortcuts, bypassing...

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Detalles Bibliográficos
Publicado en:Biotechnol Biofuels
Main Authors: Sammond, Deanne W., Kastelowitz, Noah, Donohoe, Bryon S., Alahuhta, Markus, Lunin, Vladimir V., Chung, Daehwan, Sarai, Nicholas S., Yin, Hang, Mittal, Ashutosh, Himmel, Michael E., Guss, Adam M., Bomble, Yannick J.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2018
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036693/
https://ncbi.nlm.nih.gov/pubmed/30002729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-018-1178-9
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