An iterative computational design approach to increase the thermal endurance of a mesophilic enzyme

BACKGROUND: Strategies for maximizing the microbial production of bio-based chemicals and fuels include eliminating branched points to streamline metabolic pathways. While this is often achieved by removing key enzymes, the introduction of nonnative enzymes can provide metabolic shortcuts, bypassing...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biotechnol Biofuels
Prif Awduron: Sammond, Deanne W., Kastelowitz, Noah, Donohoe, Bryon S., Alahuhta, Markus, Lunin, Vladimir V., Chung, Daehwan, Sarai, Nicholas S., Yin, Hang, Mittal, Ashutosh, Himmel, Michael E., Guss, Adam M., Bomble, Yannick J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2018
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036693/
https://ncbi.nlm.nih.gov/pubmed/30002729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-018-1178-9
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