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The distribution of ligand-binding pockets around protein-protein interfaces suggests a general mechanism for pocket formation

Protein-protein and protein-ligand interactions are ubiquitous in a biological cell. Here, we report a comprehensive study of the distribution of protein-ligand interaction sites, namely ligand-binding pockets, around protein-protein interfaces where protein-protein interactions occur. We inspected...

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Bibliografiske detaljer
Main Authors: Gao, Mu, Skolnick, Jeffrey
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309739/
https://ncbi.nlm.nih.gov/pubmed/22355140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117768109
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