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Are predicted protein structures of any value for binding site prediction and virtual ligand screening?

The recently developed field of ligand homology modeling, LHM, that extends the ideas of protein homology modeling to the prediction of ligand binding sites and for use in virtual ligand screening has emerged as a powerful new approach. Unlike traditional docking methodologies, LHM can be applied to...

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Detaylı Bibliyografya
Asıl Yazarlar: Skolnick, Jeffrey, Zhou, Hongyi, Gao, Mu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659186/
https://ncbi.nlm.nih.gov/pubmed/23415854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2013.01.009
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