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The distribution of ligand-binding pockets around protein-protein interfaces suggests a general mechanism for pocket formation
Protein-protein and protein-ligand interactions are ubiquitous in a biological cell. Here, we report a comprehensive study of the distribution of protein-ligand interaction sites, namely ligand-binding pockets, around protein-protein interfaces where protein-protein interactions occur. We inspected...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3309739/ https://ncbi.nlm.nih.gov/pubmed/22355140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117768109 |
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