Effects of Angiopoietin-2-Blocking Antibody on Endothelial Cell–Cell Junctions and Lung Metastasis

BACKGROUND: Angiopoietin-2 (Ang2), a ligand for endothelial TEK (Tie2) tyrosine kinase receptor, is induced in hypoxic endothelial cells of tumors, where it promotes tumor angiogenesis and growth. However, the effects of Ang2 on tumor lymphangiogenesis and metastasis are poorly characterized. METHOD...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Holopainen, Tanja, Saharinen, Pipsa, D’Amico, Gabriela, Lampinen, Anita, Eklund, Lauri, Sormunen, Raija, Anisimov, Andrey, Zarkada, Georgia, Lohela, Marja, Heloterä, Hanna, Tammela, Tuomas, Benjamin, Laura E., Ylä-Herttuala, Seppo, Leow, Ching Ching, Koh, Gou Young, Alitalo, Kari
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2012
Teme:
Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309130/
https://ncbi.nlm.nih.gov/pubmed/22343031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djs009
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items