Tie1 controls angiopoietin function in vascular remodeling and inflammation

The angiopoietin/Tie (ANG/Tie) receptor system controls developmental and tumor angiogenesis, inflammatory vascular remodeling, and vessel leakage. ANG1 is a Tie2 agonist that promotes vascular stabilization in inflammation and sepsis, whereas ANG2 is a context-dependent Tie2 agonist or antagonist....

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Korhonen, Emilia A., Lampinen, Anita, Giri, Hemant, Anisimov, Andrey, Kim, Minah, Allen, Breanna, Fang, Shentong, D’Amico, Gabriela, Sipilä, Tuomas J., Lohela, Marja, Strandin, Tomas, Vaheri, Antti, Ylä-Herttuala, Seppo, Koh, Gou Young, McDonald, Donald M., Alitalo, Kari, Saharinen, Pipsa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004934/
https://ncbi.nlm.nih.gov/pubmed/27548530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84923
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