Effects of Angiopoietin-2-Blocking Antibody on Endothelial Cell–Cell Junctions and Lung Metastasis

BACKGROUND: Angiopoietin-2 (Ang2), a ligand for endothelial TEK (Tie2) tyrosine kinase receptor, is induced in hypoxic endothelial cells of tumors, where it promotes tumor angiogenesis and growth. However, the effects of Ang2 on tumor lymphangiogenesis and metastasis are poorly characterized. METHOD...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Holopainen, Tanja, Saharinen, Pipsa, D’Amico, Gabriela, Lampinen, Anita, Eklund, Lauri, Sormunen, Raija, Anisimov, Andrey, Zarkada, Georgia, Lohela, Marja, Heloterä, Hanna, Tammela, Tuomas, Benjamin, Laura E., Ylä-Herttuala, Seppo, Leow, Ching Ching, Koh, Gou Young, Alitalo, Kari
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309130/
https://ncbi.nlm.nih.gov/pubmed/22343031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djs009
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados