Optimization of 2,4-Diarylanilines as Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors

The current optimization of 2,4-diarylaniline analogs (DAANs) on the central phenyl ring provided a series of new active DAAN derivatives 9a–9e, indicating an accessible modification approach that could improve anti-HIV potency against wild-type and resistant strains, aqueous solubility, and metabol...

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Hlavní autoři: Sun, Lian-Qi, Qin, Bingjie, Huang, Li, Qian, Keduo, Chen, Chin-Ho, Lee, Kuo-Hsiung, Xie, Lan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309038/
https://ncbi.nlm.nih.gov/pubmed/22406117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.02.055
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