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Design, Synthesis, and Evaluation of Diarylpyridines and Diarylanilines as Potent Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors

Based on the structures and activities of our previously identified non-nucleoside reverse transcriptase inhibitors (NNRTIs), we designed and synthesized two sets of derivatives, diarylpyridines (A) and diarylanilines (B), and tested their anti-HIV-1 activity against infection by HIV-1 NL4-3 and III...

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Detalhes bibliográficos
Main Authors: Tian, Xingtao, Qin, Bingjie, Wu, Zhiyuan, Wang, Xiaofeng, Lu, Hong, Morris-Natschke, Susan L., Chen, Chin Ho, Jiang, Shibo, Lee, Kuo-Hsiung, Xie, Lan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050082/
https://ncbi.nlm.nih.gov/pubmed/21049929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm100738d
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