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Phosphatidylserine Binding Is Essential for Plasma Membrane Recruitment and Signaling Function of 3-Phosphoinositide-dependent Kinase-1

3-Phosphoinositide-dependent kinase-1 (PDK1) is a ubiquitously expressed serine/threonine kinase that functions downstream of phosphoinositide 3-kinase. Although binding of 3′-phosphoinositides, phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,4-bisphosphate, to the pleckstrin hom...

詳細記述

保存先:
書誌詳細
主要な著者: Lucas, Nathan, Cho, Wonhwa
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308839/
https://ncbi.nlm.nih.gov/pubmed/21971045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.300806
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