Phosphoinositide 3-Kinase–Dependent Membrane Recruitment of P62(dok) Is Essential for Its Negative Effect on Mitogen-Activated Protein (Map) Kinase Activation

A major pathway by which growth factors, such as platelet-derived growth factor (PDGF), regulate cell proliferation is via the receptor tyrosine kinase/Ras/mitogen-activated protein kinase (MAPK) signaling cascade. The output of this pathway is subjected to tight regulation of both positive and nega...

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Detalhes bibliográficos
Main Authors: Zhao, Mingming, Schmitz, Arndt A.P., Qin, Yi, Di Cristofano, Antonio, Pandolfi, Pier Paolo, Van Aelst, Linda
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193463/
https://ncbi.nlm.nih.gov/pubmed/11489946
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