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FoxO1 Protein Cooperates with ATF4 Protein in Osteoblasts to Control Glucose Homeostasis
The Forkhead transcription factor FoxO1 inhibits through its expression in osteoblasts β-cell proliferation, insulin secretion, and sensitivity. At least part of the FoxO1 metabolic functions result from its ability to suppress the activity of osteocalcin, an osteoblast-derived hormone favoring gluc...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3308768/ https://ncbi.nlm.nih.gov/pubmed/22298775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.282897 |
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