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Separating planar cell polarity and Hippo pathway activities of the protocadherins Fat and Dachsous

The giant Drosophila protocadherin Fat (Ft) affects planar cell polarity (PCP). Ft also inhibits the overgrowth of imaginal discs via the Hippo pathway, repressing the activity of the transcription co-factor Yorkie (Yki). Much of Ft activity is likely to be mediated by its intracellular domain (Ft I...

詳細記述

保存先:
書誌詳細
主要な著者: Matakatsu, Hitoshi, Blair, Seth S.
フォーマット: Artigo
言語:Inglês
出版事項: Company of Biologists 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308182/
https://ncbi.nlm.nih.gov/pubmed/22399682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.070367
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