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Propagation of Dachsous-Fat Planar Cell Polarity

The Fat pathway controls both planar cell polarity (PCP) and organ growth [1, 2]. Fat signaling is regulated by the graded expression of the Fat ligand Dachsous (Ds), and the cadherin-domain kinase Four-jointed (Fj). The vectors of these gradients influence PCP [1], whereas their slope can influence...

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Detalhes bibliográficos
Main Authors: Ambegaonkar, Abhijit A., Pan, Guohui, Mani, Madhav, Feng, Yongqiang, Irvine, Kenneth D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418676/
https://ncbi.nlm.nih.gov/pubmed/22727698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.05.049
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